Orion Bionetworks leads cooperative teams to combine synergistic expertise around biomarkers, disease system biology, high performance computing information technology and big data analytics to integrate and interpret clinical, molecular, imaging and real-world patient data to develop new predictive models for brain disease.
Orion Bionetworks serves as a trusted, third-party to define a roadmap for program activities, manage diverse stakeholder interests, and ensure on-time and high-quality delivery of results.
Programs are managed by Orion’s Bionetworks’ Executive Team through a cooperative model of engagement with Alliance Partners.
Orion Bionetworks arranges bilateral agreements with all Alliance Partners to ensure alignment of data, privacy, publication and intellectual property policies across stakeholder interests.
Open-Science Framework
Orion Bionetworks along with Scientists everywhere is embracing a more open, collaborative approach to research that transcends the walls of individual laboratories and builds connections across disciplines, geographies and industries. This type of multi-stakeholder collaboration will accelerate our collective intelligence about disease.
- Generate and Share Data
- Generate and Share Tools
- Generate and Share Models
- Create Insight
Translation: Bench to Bedside
Orion Bionetworks’ core objectives include the translation of basic research to next-generation diagnostics, treatments and cures. Collaboration between the public and private sectors is an essential ingredient in this process. Better patient care relies on the establishment of a Path to Commercialization.
Investment in Brain Disease development programs has been waning in the face of high risk and low probability of success.
Orion is addressing these challenges by utilizing a Public-Private Partnership Model approach where Costs, Risks and Rewards are shared including the identification and securing of intellectual property (IP), when needed.

